| Statin-Induced Autoimmune Necrotizing Myopathy Responsive toImmunosuppressive Therapy |
| Young-Eun Park, Jae-Deuk Seo, and Dae-Seong Kim |
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| Copyright © 2012 The Korean Society of Clinical Neurophysiology |
| This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium,
provided the original work is properly cited. |
| ABSTRACT |
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Statin is commonly used for lowering cholesterols and can be myotoxic to cause drug-induced necrotizing myopathy. Statininducedmyopathy ranges from asymptomatic hyperCKemia to lethal rhabdomyolysis but is usually reversed by withdrawalof causative drugs. The patient in this study presented with statin-induced necrotizing myopathy, which was finally improvedwith immunosuppressive therapy, but not just with drug withdrawal. Since statin can induce myopathy through autoimmuneprocesses, we should consider using immunomodulating agents in cases with statin-induced myopathy, which is refractoryto drug withdrawal. |
| Key words:
Statin, Autoimmune necrotizing myopathy, Immunosuppression |
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